Dangerous Goods List (ADR, Chap. The CLP Regulation ensures that the hazards presented by chemicals are clearly communicated to workers and consumers in the European Union through classification and labelling of chemicals. Note that for readability purposes, only the pictograms, signal words and hazard statements referred in more than 5% of the notifications under CLP are displayed. Substances for which an agreed set of classification and labelling data has been agreed at EU level by Member States. It was first synthesized in 1898 by Adolph Frank and Nikodem Caro (Frank-Caro process). A series of novel guanidine derivatives were synthesized in three steps and their anti-inflammatory activities in vitro and in vivo evaluated. Signal Word. [fertilizer] [Note: Commercial grades may contain calcium carbide.] [10] The product is cooled to ambient temperatures and any unreacted carbide is leached out cautiously with water. Calcium cyanamide is a white (gray or black if impure) solid, which reacts with water. The conversion is conducted in slurries, consequently most commercial calcium cyanamide is sold as an aqueous solution. 23 0 obj <> endobj It is known to cause alcohol intolerance, before or after the consumption of alcohol. Release to the environment of this substance can occur from industrial use: formulation of mixtures. inside a watch) or with very low concentrations considered not to pose risks to human health or the environment. If a substance is classified under multiple CLH entries, a link to the C&L Inventory is provided to allow users to view CLH information associated with the substance and no text is automatically generated for the InfoCard. 40 0 obj <>/Filter/FlateDecode/ID[<88BF94CF5C2A7544AA6A1BB64B6BF538>]/Index[23 30]/Info 22 0 R/Length 85/Prev 45598/Root 24 0 R/Size 53/Type/XRef/W[1 2 1]>>stream The molecular structure is based on structures generated from information available in ECHA’s databases. The CAS number is the substance numerical identifier assigned by the Chemical Abstracts Service, a division of the American Chemical Society, to substances registered in the CAS registry database. Thiourea can be produced by the reaction of hydrogen sulfide with calcium cyanamide in the presence of carbon dioxide.[13]. Calcium cyanamide is prepared from calcium carbide. This section is based on three sources for information (harmonised classification and labelling (CLH), REACH registrations and CLP notifications). 38(12) , 1552-60, (2012). Vannerberg, N.G. The ‘Properties of concern’ section shows ECHA-assigned graphical indicators for certain substance properties that are regarded as being of relevance or importance to human health and/or the environment based on the information provided to the Agency. Teerfarbenfabr. Since calcium cyanamide reacts with oxygen at high temperatures, all of these routes must be done in the absence of oxygen, thus an inert gas is often used. The CLP Regulation makes sure that the hazards presented by chemicals are clearly communicated to workers and consumers in the European Union. Empty paint or instant coffee cans are good. calcium cyanamide structure. This information is only displayed if the substance is well-defined, its identity is not claimed confidential and there is sufficient information available in ECHA’s databases for ECHA’s algorithms to generate a molecular structure. Derivatives of this compound are also referred to as cyanamides, the most common being calcium cyanamide (CaCN 2 ). Pure calcium cyanamide occurs as glistening hexagonal crystals that are insoluble in water. This process requires meticulous temperature control since the melting point of calcium cyanamide is only about 120°C lower than the boiling point of sodium chloride. Occupational exposure limit (OEL) values are derived within two legal frameworks that form an integral part of the EU’s mechanism for protecting the health of workers. [7] Frank and Caro also noted the formation of ammonia from calcium cyanamide.[8]. More information about the EC Inventory can be found here. Calcium cyanamide is the inorganic compound with the formula CaCN2. The REACH registered substance data and the C&L Inventory portal will be upgraded from the 9th November. [4], In their search for a new process for producing cyanides for cyanide leaching of gold, Frank and Caro discovered the ability of alkaline earth carbides to adsorb atmospheric nitrogen at high temperatures. "The crystal structure of calcium cyanamide" Acta Chemica Scandinavica (1-27,1973-42,1988) (1962) 16, p2263-p2266, National Institute for Occupational Safety and Health, "Effect of calcium cyanamide on growth and nutrition of plan fed yellow-poplar seedlings", "History of Degussa: Rich harvest, healthy environment", "Commercialization of Calcium Carbide and Acetylene - Landmark", Scientific Committee on Health and Environmental Risks, Bioassay of Calcium Cyanamide for Possible Carcinogenicity (CAS No.